Heh, agree with your thoughts on Explosm, VG Cats, and CAD (I haven't really read much of the others). VG Cats used to be my favorite and I thought it was friggin hilarious. Maybe I guess at the time thier comics came out, I was playing the games that were the subject of the jokes. The pokemon ones stick out as well as the unreal tournament one. Explosm comics aren't as well thought-out as VG Cats imo, but some of them make me burst out laughing. And CAD ... well they are just awful. You can tell your comic sucks when you have to explain the joke in the last panel.
I agree with your thoughts of CAD... someone told me they were really funny, but I got bored very quick... I couldn't find a good one
Most Explosm comics seem to be drawn while very drunk... but I find them funny...
And VG cats is funny too, but they never actualize. I had a lot of hopes in their pokemon red/blue comic, but they stopped updating again